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FSCH-SE-196176

The role of acidosis-sensing in the regulation of chronic inflammation by skeletal muscle
Safia Sabr Ibrahim
Department of Medical Microbiology, Faculty of Sceince and Health, Koya University
http://koyauniversity.org

Abstract: Many chronic inflammatory diseases including CKD are characterised by loss of muscle or cachexia. Cachexia is multifactor syndrome characterised by severe (up to 75%) skeletal muscle wasting, muscle wasting leads to decrease mobility and quality of life and increase the mortality rate. While chronic inflammation can cause cachexia, loss of skeletal muscle can also contribute to inflammation. Skeletal muscle cells can produce anti-inflammatory cytokines.

KeywordsAcidosis, Cachexia, Chronic Kidney disease, Phosphorylation.


Date: 03/02/2020
Place: Department of Medical Microbiology/ Hall No.14
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Caroline Yousif Daniel,
Mar 22, 2020, 11:46 AM